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When it comes to mutations in Fallout 76, few things are as game-changing as serums. These consumables give players instant access to powerful mutations without relying on the randomness of radiation exposure. For players looking to maximize builds or experiment with unique playstyles, knowing the List of Fallout 76 Serums and their effects is essential.

What Are Serums in Fallout 76?

Serums are consumable items crafted at chemistry benches that grant a specific mutation immediately upon use. Unlike radiation-based mutations, serums provide a guaranteed outcome, which makes them especially valuable for players chasing specific builds. They also come with a temporary buff that reduces the negative side effects of the mutation for one hour.

The Full List of Fallout 76 Serums

Below is the List of Fallout 76 Serums currently available in the game, each tied to a mutation with unique benefits and drawbacks:

• Adrenal Reaction Serum – Increases weapon damage as health decreases, but reduces overall health.

• Bird Bones Serum – Grants slower falling speed and improved agility, but lowers strength.

• Carnivore Serum – Doubles benefits from meat-based food, but disables plant-based food bonuses.

• Chameleon Serum – Provides invisibility while standing still and not wearing armor.

• Eagle Eyes Serum – Boosts perception and critical damage, but lowers strength.

• Egg Head Serum – Raises intelligence, but reduces strength and endurance.

• Empath Serum – Decreases damage taken by teammates, but increases damage taken by you.

• Grounded Serum – Adds energy resistance, but reduces energy weapon damage.

• Healing Factor Serum – Greatly increases health regeneration, but reduces chem effectiveness.

• Herbivore Serum – Doubles benefits from plant-based food, but disables meat-based bonuses.

• Marsupial Serum – Increases carry weight and jump height, but lowers intelligence.

• Plague Walker Serum – Emits a damaging aura when infected with disease.

• Scaly Skin Serum – Improves damage and energy resistance, but lowers action point regeneration.

• Speed Demon Serum – Increases movement and reload speed, but boosts hunger and thirst drain.

• Talons Serum – Adds bleed damage to unarmed attacks, but prevents using weapons effectively.

• Twisted Muscles Serum – Increases melee damage, but decreases accuracy with ranged weapons.

• Unstable Isotope Serum – Causes radiation damage to melee attackers.

Where to Get Serums

Serums can be crafted at chemistry stations if you own the plans, or purchased from specific vendors such as MODUS in the Whitespring Bunker. Plans are expensive, often costing thousands of caps, but once unlocked, they provide unlimited crafting potential as long as you have the ingredients.

Best Serums for Different Builds

• Marsupial is nearly universal for extra mobility and inventory space.

• Speed Demon is popular with ranged and heavy weapon users due to faster reloads.

• Adrenal Reaction works well with bloodied builds that thrive on low health.

• Carnivore or Herbivore are fantastic for food-focused survival builds.

Serums remain one of the most versatile tools in Fallout 76’s build system. Whether you want to specialize in stealth, melee combat, or survival efficiency, knowing the full List of Fallout 76 Serums gives you the flexibility to experiment and fine-tune your character. If you’re aiming for a high-level build, investing in serums is one of the best long-term decisions you can make.