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5. During Long, Protracted Fights (PvE or PvP)
In long fights, such as PvE boss battles or PvP fights that drag on, Call of the Ancients provides sustained support for both survivability and Diablo 4 Items offensive output. Rather than using it at the very start of the fight, consider using it midway through when the fight’s intensity is ramping up, and your Fury and cooldowns are about to line up for another big burst.

Why It Works:
Sustained Buffs: The Ancients continue to provide offensive and defensive buffs throughout the fight, ensuring you’re always maximizing your potential damage.
Constant Pressure: The longer the fight goes, the more value you get out of Call of the Ancients, making it easier to sustain your offense and keep up the pressure.
How to Use It:
Save Call of the Ancients for a mid-fight activation when you anticipate the need for extra damage mitigation and when your Fury generation is stable enough to maximize your Upheaval burst.
Pair with other cooldowns, like Rallying Cry or War Cry, to create a perfect synergy that keeps you at full power.
Conclusion: Mastering the Timing of Call of the Ancients
The key to maximizing Call of the Ancients in your Upheaval Barbarian build is understanding the right moments to use it during combat. Whether you’re facing PvE bosses, endgame dungeons, or PvP encounters, the Ancients offer significant advantages for both survivability and damage output. By strategically activating this skill at key moments — such as during burst phases, when facing heavy damage, or to cheap Diablo 4 Items resist crowd control — you can make the most out of Call of the Ancients and truly become an unstoppable force in Diablo 4.

During Long, Protracted Fights (PvE or PvP): Leveraging Call of the Ancients
In long, protracted fights, whether in PvE (such as endgame boss battles or high-tier dungeons) or PvP (like drawn-out skirmishes with enemy players), managing your resources and keeping up constant pressure is crucial. In these situations, Call of the Ancients serves as a versatile tool to both enhance survivability and maintain consistent damage output. Here’s how to make the most of Call of the Ancients during long battles: